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HURP permits MTOC sorting for robust meiotic spindle bipolarity, similar to extra centrosome clustering in cancer cells
In contrast to somatic cells, formation of acentriolar meiotic spindles relies on the organization of microtubules (MTs) and MT-organizing centers (MTOCs) into a stable bipolar structure. The underlying mechanisms are still unknown. We show that this process is impaired in hepatoma up-regulated prot...
Autores principales: | Breuer, Manuel, Kolano, Agnieszka, Kwon, Mijung, Li, Chao-Chin, Tsai, Ting-Fen, Pellman, David, Brunet, Stéphane, Verlhac, Marie-Hélène |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010075/ https://www.ncbi.nlm.nih.gov/pubmed/21173113 http://dx.doi.org/10.1083/jcb.201005065 |
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