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Sex differences in renal angiotensin converting enzyme 2 (ACE2) activity are 17β-oestradiol-dependent and sex chromosome-independent

BACKGROUND: Angotensin converting enzyme 2 (ACE2) is a newly discovered monocarboxypeptidase that counteracts the vasoconstrictor effects of angiotensin II (Ang II) by converting Ang II to Ang-(1-7) in the kidney and other tissues. METHODS: ACE2 activity from renal homogenates was investigated by us...

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Detalles Bibliográficos
Autores principales: Liu, Jun, Ji, Hong, Zheng, Wei, Wu, Xie, Zhu, Janet J, Arnold, Arthur P, Sandberg, Kathryn
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010099/
https://www.ncbi.nlm.nih.gov/pubmed/21208466
http://dx.doi.org/10.1186/2042-6410-1-6