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Unraveling condition-dependent networks of transcription factors that control metabolic pathway activity in yeast

Which transcription factors control the distribution of metabolic fluxes under a given condition? We address this question by systematically quantifying metabolic fluxes in 119 transcription factor deletion mutants of Saccharomyces cerevisiae under five growth conditions. While most knockouts did no...

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Detalles Bibliográficos
Autores principales: Fendt, Sarah-Maria, Oliveira, Ana Paula, Christen, Stefan, Picotti, Paola, Dechant, Reinhard Christoph, Sauer, Uwe
Formato: Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010106/
https://www.ncbi.nlm.nih.gov/pubmed/21119627
http://dx.doi.org/10.1038/msb.2010.91