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Three serendipitous pathways in E. coli can bypass a block in pyridoxal-5′-phosphate synthesis
Bacterial genomes encode hundreds to thousands of enzymes, most of which are specialized for particular functions. However, most enzymes have inefficient promiscuous activities, as well, that generally serve no purpose. Promiscuous reactions can be patched together to form multistep metabolic pathwa...
Autores principales: | Kim, Juhan, Kershner, Jamie P, Novikov, Yehor, Shoemaker, Richard K, Copley, Shelley D |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
European Molecular Biology Organization
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010111/ https://www.ncbi.nlm.nih.gov/pubmed/21119630 http://dx.doi.org/10.1038/msb.2010.88 |
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