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Intra- and inter-chromosomal interactions correlate with CTCF binding genome wide

A prime goal in systems biology is the comprehensive use of existing high-throughput genomic datasets to gain a better understanding of chromatin organization and genome function. In this report, we use chromatin immunoprecipitation (ChIP) data that map protein-binding sites on the genome, and Hi-C...

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Detalles Bibliográficos
Autores principales: Botta, Marco, Haider, Syed, Leung, Ian X Y, Lio, Pietro, Mozziconacci, Julien
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010120/
https://www.ncbi.nlm.nih.gov/pubmed/21045820
http://dx.doi.org/10.1038/msb.2010.79