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Inflammation, HIF-1, and the Epigenetics That Follows

We summarize recent findings linking inflammatory hypoxia to chromatin modifications, in particular to repressive histone signatures. We focus on the role of Hypoxia-Induced Factor-1 in promoting the activity of specific histone demethylases thus deeply modifying chromatin configuration. The consequ...

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Detalles Bibliográficos
Autores principales: Brigati, Claudio, Banelli, Barbara, di Vinci, Angela, Casciano, Ida, Allemanni, Giorgio, Forlani, Alessandra, Borzì, Luana, Romani, Massimo
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010677/
https://www.ncbi.nlm.nih.gov/pubmed/21197398
http://dx.doi.org/10.1155/2010/263914