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BAC Modification through Serial or Simultaneous Use of CRE/Lox Technology
Bacterial Artificial Chromosomes (BACs) are vital tools in mouse genomic analyses because of their ability to propagate large inserts. The size of these constructs, however, prevents the use of conventional molecular biology techniques for modification and manipulation. Techniques such as recombinee...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010708/ https://www.ncbi.nlm.nih.gov/pubmed/21197414 http://dx.doi.org/10.1155/2011/924068 |