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Novel Perspectives on p53 Function in Neural Stem Cells and Brain Tumors

Malignant glioma is the most common brain tumor in adults and is associated with a very poor prognosis. Mutations in the p53 tumor suppressor gene are frequently detected in gliomas. p53 is well-known for its ability to induce cell cycle arrest, apoptosis, senescence, or differentiation following ce...

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Detalles Bibliográficos
Autores principales: Hede, Sanna-Maria, Nazarenko, Inga, Nistér, Monica, Lindström, Mikael S.
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010739/
https://www.ncbi.nlm.nih.gov/pubmed/21209724
http://dx.doi.org/10.1155/2011/852970