Pairwise Agonist Scanning of human platelets reveals the high-dimensional calcium response to combinatorial mediators of thrombosis

Patient-specific prediction of cellular response to multiple stimuli is central to evaluating clinical risk, disease progression, and response to therapy. We deployed Pairwise Agonist Scanning (PAS) to measure calcium signaling of human platelets in EDTA-treated plasma exposed to 6 different agonist...

Descripción completa

Detalles Bibliográficos
Autores principales: Chatterjee, Manash S., Purvis, Jeremy E., Brass, Lawrence F., Diamond, Scott L.
Formato: Texto
Lenguaje:English
Publicado: 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010846/
https://www.ncbi.nlm.nih.gov/pubmed/20562863
http://dx.doi.org/10.1038/nbt.1642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010846/
https://www.ncbi.nlm.nih.gov/pubmed/20562863
http://dx.doi.org/10.1038/nbt.1642

Ejemplares similares