Ligand-Induced Tyrosine Phosphorylation of Cysteinyl Leukotriene Receptor 1 Triggers Internalization and Signaling in Intestinal Epithelial Cells

BACKGROUND: Leukotriene D(4) (LTD(4)) belongs to the bioactive lipid group known as eicosanoids and has implications in pathological processes such as inflammation and cancer. Leukotriene D(4) exerts its effects mainly through two different G-protein-coupled receptors, CysLT(1) and CysLT(2). The hig...

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Detalles Bibliográficos
Autores principales: Parhamifar, Ladan, Sime, Wondossen, Yudina, Yuliana, Vilhardt, Frederik, Mörgelin, Matthias, Sjölander, Anita
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010979/
https://www.ncbi.nlm.nih.gov/pubmed/21203429
http://dx.doi.org/10.1371/journal.pone.0014439

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010979/
https://www.ncbi.nlm.nih.gov/pubmed/21203429
http://dx.doi.org/10.1371/journal.pone.0014439

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