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RAF Kinase Activity Regulates Neuroepithelial Cell Proliferation and Neuronal Progenitor Cell Differentiation during Early Inner Ear Development

BACKGROUND: Early inner ear development requires the strict regulation of cell proliferation, survival, migration and differentiation, coordinated by the concerted action of extrinsic and intrinsic factors. Deregulation of these processes is associated with embryonic malformations and deafness. We h...

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Detalles Bibliográficos
Autores principales: Magariños, Marta, Aburto, María R., Sánchez-Calderón, Hortensia, Muñoz-Agudo, Carmen, Rapp, Ulf R., Varela-Nieto, Isabel
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010996/
https://www.ncbi.nlm.nih.gov/pubmed/21203386
http://dx.doi.org/10.1371/journal.pone.0014435