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RAF Kinase Activity Regulates Neuroepithelial Cell Proliferation and Neuronal Progenitor Cell Differentiation during Early Inner Ear Development
BACKGROUND: Early inner ear development requires the strict regulation of cell proliferation, survival, migration and differentiation, coordinated by the concerted action of extrinsic and intrinsic factors. Deregulation of these processes is associated with embryonic malformations and deafness. We h...
Autores principales: | Magariños, Marta, Aburto, María R., Sánchez-Calderón, Hortensia, Muñoz-Agudo, Carmen, Rapp, Ulf R., Varela-Nieto, Isabel |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3010996/ https://www.ncbi.nlm.nih.gov/pubmed/21203386 http://dx.doi.org/10.1371/journal.pone.0014435 |
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