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In Vivo Assessment of Parenteral Formulations of Oligo(3-Hydroxybutyric Acid) Conjugates with the Model Compound Ibuprofen

Polymer-drug conjugates have gained significant attention as pro-drugs releasing an active substance as a result of enzymatic hydrolysis in physiological environment. In this study, a conjugate of 3-hydroxybutyric acid oligomers with a carboxylic acid group-bearing model drug (ibuprofen) was evaluat...

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Detalles Bibliográficos
Autores principales: Stasiak, Pawel, Sznitowska, Malgorzata, Ehrhardt, Carsten, Luczyk-Juzwa, Maria, Grieb, Pawel
Formato: Texto
Lenguaje:English
Publicado: Springer US 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011063/
https://www.ncbi.nlm.nih.gov/pubmed/21088943
http://dx.doi.org/10.1208/s12249-010-9545-2