Novel animal models for studying complex brain disorders: BAC-driven miRNA-mediated in vivo silencing of gene expression

In schizophrenia, glutamic acid decarboxylase 1 (GAD1) disturbances are robust, consistently observed, cell-type specific and represent a core feature of the disease. In addition, neuropeptide Y (NPY), which is a phenotypic marker of a sub-population of GAD1-containing interneurons, has shown reduce...

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Detalles Bibliográficos
Autores principales: Garbett, K A, Horváth, S, Ebert, P J, Schmidt, M J, Lwin, K, Mitchell, A, Levitt, P, Mirnics, K
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011211/
https://www.ncbi.nlm.nih.gov/pubmed/20125089
http://dx.doi.org/10.1038/mp.2010.1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3011211/
https://www.ncbi.nlm.nih.gov/pubmed/20125089
http://dx.doi.org/10.1038/mp.2010.1

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