A Systematic Enhancer Screen Using Lentivector Transgenesis Identifies Conserved and Non-Conserved Functional Elements at the Olig1 and Olig2 Locus

Finding sequences that control expression of genes is central to understanding genome function. Previous studies have used evolutionary conservation as an indicator of regulatory potential. Here, we present a method for the unbiased in vivo screen of putative enhancers in large DNA regions, using th...

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Detalles Bibliográficos
Autores principales: Friedli, Marc, Barde, Isabelle, Arcangeli, Mélanie, Verp, Sonia, Quazzola, Alexandra, Zakany, Jozsef, Lin-Marq, Nathalie, Robyr, Daniel, Attanasio, Catia, Spitz, François, Duboule, Denis, Trono, Didier, Antonarakis, Stylianos E.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012086/
https://www.ncbi.nlm.nih.gov/pubmed/21206754
http://dx.doi.org/10.1371/journal.pone.0015741

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012086/
https://www.ncbi.nlm.nih.gov/pubmed/21206754
http://dx.doi.org/10.1371/journal.pone.0015741

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