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The Effect of Micrococcal Nuclease Digestion on Nucleosome Positioning Data
Eukaryotic genomes are packed into chromatin, whose basic repeating unit is the nucleosome. Nucleosome positioning is a widely researched area. A common experimental procedure to determine nucleosome positions involves the use of micrococcal nuclease (MNase). Here, we show that the cutting preferenc...
Autores principales: | , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012088/ https://www.ncbi.nlm.nih.gov/pubmed/21206756 http://dx.doi.org/10.1371/journal.pone.0015754 |