Coordinated Translocation of Mammalian Gli Proteins and Suppressor of Fused to the Primary Cilium

Intracellular transduction of Hedgehog (Hh) signals in mammals requires functional primary cilia. The Hh signaling effectors, the Gli family of transcription factors, and their negative regulator, Suppressor of Fused (Sufu), accumulate at the tips of cilia; however, the molecular mechanism regulatin...

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Detalles Bibliográficos
Autores principales: Zeng, Huiqing, Jia, Jinping, Liu, Aimin
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012114/
https://www.ncbi.nlm.nih.gov/pubmed/21209912
http://dx.doi.org/10.1371/journal.pone.0015900

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012114/
https://www.ncbi.nlm.nih.gov/pubmed/21209912
http://dx.doi.org/10.1371/journal.pone.0015900

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