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Comparative Magnitude of Cross-Strain Conservation of HIV Variable Loop Neutralization Epitopes

Although the sequence variable loops of the human immunodeficiency virus' (HIV-1) surface envelope glycoprotein (gp120) can exhibit good immunogenicity, characterizing conserved (invariant) cross-strain neutralization epitopes within these loops has proven difficult. We recently developed a met...

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Detalles Bibliográficos
Autores principales: Swetnam, James, Shmelkov, Evgeny, Zolla-Pazner, Susan, Cardozo, Timothy
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012121/
https://www.ncbi.nlm.nih.gov/pubmed/21209919
http://dx.doi.org/10.1371/journal.pone.0015994