Cargando…
Lack of TRPM2 Impaired Insulin Secretion and Glucose Metabolisms in Mice
OBJECTIVE: TRPM2 is a Ca(2+)-permeable nonselective cation channel activated by adenosine dinucleotides. We previously demonstrated that TRPM2 is activated by coapplication of heat and intracellular cyclic adenosine 5′-diphosphoribose, which has been suggested to be involved in intracellular Ca(2+)...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012163/ https://www.ncbi.nlm.nih.gov/pubmed/20921208 http://dx.doi.org/10.2337/db10-0276 |