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Lack of TRPM2 Impaired Insulin Secretion and Glucose Metabolisms in Mice

OBJECTIVE: TRPM2 is a Ca(2+)-permeable nonselective cation channel activated by adenosine dinucleotides. We previously demonstrated that TRPM2 is activated by coapplication of heat and intracellular cyclic adenosine 5′-diphosphoribose, which has been suggested to be involved in intracellular Ca(2+)...

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Detalles Bibliográficos
Autores principales:	Uchida, Kunitoshi, Dezaki, Katsuya, Damdindorj, Boldbaatar, Inada, Hitoshi, Shiuchi, Tetsuya, Mori, Yasuo, Yada, Toshihiko, Minokoshi, Yasuhiko, Tominaga, Makoto
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2011
Materias:	Signal Transduction
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012163/ https://www.ncbi.nlm.nih.gov/pubmed/20921208 http://dx.doi.org/10.2337/db10-0276

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