Diminished Superoxide Generation Is Associated With Respiratory Chain Dysfunction and Changes in the Mitochondrial Proteome of Sensory Neurons From Diabetic Rats

OBJECTIVE: Impairments in mitochondrial function have been proposed to play a role in the etiology of diabetic sensory neuropathy. We tested the hypothesis that mitochondrial dysfunction in axons of sensory neurons in type 1 diabetes is due to abnormal activity of the respiratory chain and an altere...

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Detalles Bibliográficos
Autores principales: Akude, Eli, Zherebitskaya, Elena, Chowdhury, Subir K. Roy, Smith, Darrell R., Dobrowsky, Rick T., Fernyhough, Paul
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2011
Materias:
Complications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012184/
https://www.ncbi.nlm.nih.gov/pubmed/20876714
http://dx.doi.org/10.2337/db10-0818

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012184/
https://www.ncbi.nlm.nih.gov/pubmed/20876714
http://dx.doi.org/10.2337/db10-0818

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