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Diminished Superoxide Generation Is Associated With Respiratory Chain Dysfunction and Changes in the Mitochondrial Proteome of Sensory Neurons From Diabetic Rats

OBJECTIVE: Impairments in mitochondrial function have been proposed to play a role in the etiology of diabetic sensory neuropathy. We tested the hypothesis that mitochondrial dysfunction in axons of sensory neurons in type 1 diabetes is due to abnormal activity of the respiratory chain and an altere...

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Detalles Bibliográficos
Autores principales:	Akude, Eli, Zherebitskaya, Elena, Chowdhury, Subir K. Roy, Smith, Darrell R., Dobrowsky, Rick T., Fernyhough, Paul
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2011
Materias:	Complications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012184/ https://www.ncbi.nlm.nih.gov/pubmed/20876714 http://dx.doi.org/10.2337/db10-0818

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