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ISDD: A computational model of particle sedimentation, diffusion and target cell dosimetry for in vitro toxicity studies

BACKGROUND: The difficulty of directly measuring cellular dose is a significant obstacle to application of target tissue dosimetry for nanoparticle and microparticle toxicity assessment, particularly for in vitro systems. As a consequence, the target tissue paradigm for dosimetry and hazard assessme...

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Detalles Bibliográficos
Autores principales: Hinderliter, Paul M, Minard, Kevin R, Orr, Galya, Chrisler, William B, Thrall, Brian D, Pounds, Joel G, Teeguarden, Justin G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012653/
https://www.ncbi.nlm.nih.gov/pubmed/21118529
http://dx.doi.org/10.1186/1743-8977-7-36