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CSF from Parkinson disease Patients Differentially Affects Cultured Microglia and Astrocytes

BACKGROUND: Excessive and abnormal accumulation of alpha-synuclein (α-synuclein) is a factor contributing to pathogenic cell death in Parkinson's disease. The purpose of this study, based on earlier observations of Parkinson's disease cerebrospinal fluid (PD-CSF) initiated cell death, was...

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Detalles Bibliográficos
Autores principales: Schiess, Mya C, Barnes, Jennifer L, Ellmore, Timothy M, Poindexter, Brian J, Dinh, Kha, Bick, Roger J
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012671/
https://www.ncbi.nlm.nih.gov/pubmed/21114836
http://dx.doi.org/10.1186/1471-2202-11-151