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Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis

BACKGROUND: High-throughput profiling of DNA methylation status of CpG islands is crucial to understand the epigenetic regulation of genes. The microarray-based Infinium methylation assay by Illumina is one platform for low-cost high-throughput methylation profiling. Both Beta-value and M-value stat...

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Detalles Bibliográficos
Autores principales: Du, Pan, Zhang, Xiao, Huang, Chiang-Ching, Jafari, Nadereh, Kibbe, Warren A, Hou, Lifang, Lin, Simon M
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012676/
https://www.ncbi.nlm.nih.gov/pubmed/21118553
http://dx.doi.org/10.1186/1471-2105-11-587