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Comparison of Beta-value and M-value methods for quantifying methylation levels by microarray analysis
BACKGROUND: High-throughput profiling of DNA methylation status of CpG islands is crucial to understand the epigenetic regulation of genes. The microarray-based Infinium methylation assay by Illumina is one platform for low-cost high-throughput methylation profiling. Both Beta-value and M-value stat...
Autores principales: | Du, Pan, Zhang, Xiao, Huang, Chiang-Ching, Jafari, Nadereh, Kibbe, Warren A, Hou, Lifang, Lin, Simon M |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012676/ https://www.ncbi.nlm.nih.gov/pubmed/21118553 http://dx.doi.org/10.1186/1471-2105-11-587 |
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