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Crystal Structure of UBA2(ufd)-Ubc9: Insights into E1-E2 Interactions in Sumo Pathways

Canonical ubiquitin-like proteins (UBLs) such as ubiquitin, Sumo, NEDD8, and ISG15 are ligated to targets by E1-E2-E3 multienzyme cascades. The Sumo cascade, conserved among all eukaryotes, regulates numerous biological processes including protein localization, transcription, DNA replication, and mi...

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Detalles Bibliográficos
Autores principales: Wang, Jing, Taherbhoy, Asad M., Hunt, Harold W., Seyedin, Steven N., Miller, David W., Miller, Darcie J., Huang, Danny T., Schulman, Brenda A.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012696/
https://www.ncbi.nlm.nih.gov/pubmed/21209884
http://dx.doi.org/10.1371/journal.pone.0015805