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Crystal Structure of UBA2(ufd)-Ubc9: Insights into E1-E2 Interactions in Sumo Pathways
Canonical ubiquitin-like proteins (UBLs) such as ubiquitin, Sumo, NEDD8, and ISG15 are ligated to targets by E1-E2-E3 multienzyme cascades. The Sumo cascade, conserved among all eukaryotes, regulates numerous biological processes including protein localization, transcription, DNA replication, and mi...
Autores principales: | Wang, Jing, Taherbhoy, Asad M., Hunt, Harold W., Seyedin, Steven N., Miller, David W., Miller, Darcie J., Huang, Danny T., Schulman, Brenda A. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012696/ https://www.ncbi.nlm.nih.gov/pubmed/21209884 http://dx.doi.org/10.1371/journal.pone.0015805 |
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