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Dynamics of Glycoprotein Charge in the Evolutionary History of Human Influenza

BACKGROUND: Influenza viruses show a significant capacity to evade host immunity; this is manifest both as large occasional jumps in the antigenic phenotype of viral surface molecules and in gradual antigenic changes leading to annual influenza epidemics in humans. Recent mouse studies show that avi...

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Detalles Bibliográficos
Autores principales: Arinaminpathy, Nimalan, Grenfell, Bryan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012697/
https://www.ncbi.nlm.nih.gov/pubmed/21209885
http://dx.doi.org/10.1371/journal.pone.0015674