Lysophosphatidic Acid Induces MDA-MB-231 Breast Cancer Cells Migration through Activation of PI3K/PAK1/ERK Signaling

BACKGROUND: Enhanced motility of cancer cells is a critical step in promoting tumor metastasis. Lysophosphatidic acid (LPA), representing the major mitogenic activity in serum, stimulates migration in various types of cancer cells. However, the underlying signaling mechanisms for LPA-induced motilit...

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Detalles Bibliográficos
Autores principales: Du, Jun, Sun, Chongqi, Hu, Zhenzhen, Yang, Yu, Zhu, Yichao, Zheng, Datong, Gu, Luo, Lu, Xiang
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012724/
https://www.ncbi.nlm.nih.gov/pubmed/21209852
http://dx.doi.org/10.1371/journal.pone.0015940

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012724/
https://www.ncbi.nlm.nih.gov/pubmed/21209852
http://dx.doi.org/10.1371/journal.pone.0015940

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