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The Cooperation between hMena Overexpression and HER2 Signalling in Breast Cancer

hMena and the epithelial specific isoform hMena(11a) are actin cytoskeleton regulatory proteins belonging to the Ena/VASP family. EGF treatment of breast cancer cell lines upregulates hMena/hMena(11a) expression and phosphorylates hMena(11a), suggesting cross-talk between the ErbB receptor family an...

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Detalles Bibliográficos
Autores principales: Di Modugno, Francesca, Mottolese, Marcella, DeMonte, Lucia, Trono, Paola, Balsamo, Michele, Conidi, Andrea, Melucci, Elisa, Terrenato, Irene, Belleudi, Francesca, Torrisi, Maria Rosaria, Alessio, Massimo, Santoni, Angela, Nisticò, Paola
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012725/
https://www.ncbi.nlm.nih.gov/pubmed/21209853
http://dx.doi.org/10.1371/journal.pone.0015852