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Repetitive Pertussis Toxin Promotes Development of Regulatory T Cells and Prevents Central Nervous System Autoimmune Disease

Bacterial and viral infections have long been implicated in pathogenesis and progression of multiple sclerosis (MS). Incidence and severity of its animal model experimental autoimmune encephalomyelitis (EAE) can be enhanced by concomitant administration of pertussis toxin (PTx), the major virulence...

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Detalles Bibliográficos
Autores principales: Weber, Martin S., Benkhoucha, Mahdia, Lehmann-Horn, Klaus, Hertzenberg, Deetje, Sellner, Johann, Santiago-Raber, Marie-Laure, Chofflon, Michel, Hemmer, Bernhard, Zamvil, Scott S., Lalive, Patrice H.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012729/
https://www.ncbi.nlm.nih.gov/pubmed/21209857
http://dx.doi.org/10.1371/journal.pone.0016009