The laminin β1-competing peptide YIGSR induces a hypercontractile, hypoproliferative airway smooth muscle phenotype in an animal model of allergic asthma

BACKGROUND: Fibroproliferative airway remodelling, including increased airway smooth muscle (ASM) mass and contractility, contributes to airway hyperresponsiveness in asthma. In vitro studies have shown that maturation of ASM cells to a (hyper)contractile phenotype is dependent on laminin, which can...

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Detalles Bibliográficos
Autores principales: Dekkers, Bart GJ, Bos, I Sophie T, Halayko, Andrew J, Zaagsma, Johan, Meurs, Herman
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013082/
https://www.ncbi.nlm.nih.gov/pubmed/21129174
http://dx.doi.org/10.1186/1465-9921-11-170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013082/
https://www.ncbi.nlm.nih.gov/pubmed/21129174
http://dx.doi.org/10.1186/1465-9921-11-170

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