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Expression of BMI-1 and Mel-18 in breast tissue - a diagnostic marker in patients with breast cancer

BACKGROUND: Polycomb Group (PcG) proteins are epigenetic silencers involved in maintaining cellular identity, and their deregulation can result in cancer. Expression of Mel-18 and Bmi-1 has been studied in tumor tissue, but not in adjacent non-cancerous breast epithelium. Our study compares the expr...

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Detalles Bibliográficos
Autores principales: Riis, Margit LH, Lüders, Torben, Nesbakken, Anne-Jorunn, Vollan, Hilde S, Kristensen, Vessela, Bukholm, Ida RK
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013088/
https://www.ncbi.nlm.nih.gov/pubmed/21162745
http://dx.doi.org/10.1186/1471-2407-10-686