Purging Deleterious Mutations under Self Fertilization: Paradoxical Recovery in Fitness with Increasing Mutation Rate in Caenorhabditis elegans

BACKGROUND: The accumulation of deleterious mutations can drastically reduce population mean fitness. Self-fertilization is thought to be an effective means of purging deleterious mutations. However, widespread linkage disequilibrium generated and maintained by self-fertilization is predicted to red...

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Detalles Bibliográficos
Autores principales: Morran, Levi T., Ohdera, Aki H., Phillips, Patrick C.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013097/
https://www.ncbi.nlm.nih.gov/pubmed/21217820
http://dx.doi.org/10.1371/journal.pone.0014473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013097/
https://www.ncbi.nlm.nih.gov/pubmed/21217820
http://dx.doi.org/10.1371/journal.pone.0014473

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