Re-Evaluation of the Action Potential Upstroke Velocity as a Measure of the Na(+) Current in Cardiac Myocytes at Physiological Conditions

BACKGROUND: The SCN5A encoded sodium current (I(Na)) generates the action potential (AP) upstroke and is a major determinant of AP characteristics and AP propagation in cardiac myocytes. Unfortunately, in cardiac myocytes, investigation of kinetic properties of I(Na) with near-physiological ion conc...

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Detalles Bibliográficos
Autores principales: Berecki, Géza, Wilders, Ronald, de Jonge, Berend, van Ginneken, Antoni C. G., Verkerk, Arie O.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013114/
https://www.ncbi.nlm.nih.gov/pubmed/21217835
http://dx.doi.org/10.1371/journal.pone.0015772

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013114/
https://www.ncbi.nlm.nih.gov/pubmed/21217835
http://dx.doi.org/10.1371/journal.pone.0015772

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