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Re-Evaluation of the Action Potential Upstroke Velocity as a Measure of the Na(+) Current in Cardiac Myocytes at Physiological Conditions
BACKGROUND: The SCN5A encoded sodium current (I(Na)) generates the action potential (AP) upstroke and is a major determinant of AP characteristics and AP propagation in cardiac myocytes. Unfortunately, in cardiac myocytes, investigation of kinetic properties of I(Na) with near-physiological ion conc...
| Autores principales: | , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013114/ https://www.ncbi.nlm.nih.gov/pubmed/21217835 http://dx.doi.org/10.1371/journal.pone.0015772 |