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Mutation Detection with Next-Generation Resequencing through a Mediator Genome

The affordability of next generation sequencing (NGS) is transforming the field of mutation analysis in bacteria. The genetic basis for phenotype alteration can be identified directly by sequencing the entire genome of the mutant and comparing it to the wild-type (WT) genome, thus identifying acquir...

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Detalles Bibliográficos
Autores principales: Wurtzel, Omri, Dori-Bachash, Mally, Pietrokovski, Shmuel, Jurkevitch, Edouard, Sorek, Rotem
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013116/
https://www.ncbi.nlm.nih.gov/pubmed/21209874
http://dx.doi.org/10.1371/journal.pone.0015628