Thrombin Induces Macrophage Migration Inhibitory Factor Release and Upregulation in Urothelium: A Possible Contribution to Bladder Inflammation

PURPOSE: Macrophage migration inhibitory factor (MIF) is a pro-inflammatory cytokine expressed by urothelial cells that mediates bladder inflammation. We investigated the effect of stimulation with thrombin, a Protease Activated Receptor-1 (PAR1) agonist, on MIF release and MIF mRNA upregulation in...

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Detalles Bibliográficos
Autores principales: Vera, Pedro L., Wolfe, Terra E., Braley, Alexander E., Meyer-Siegler, Katherine L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013117/
https://www.ncbi.nlm.nih.gov/pubmed/21209875
http://dx.doi.org/10.1371/journal.pone.0015904

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013117/
https://www.ncbi.nlm.nih.gov/pubmed/21209875
http://dx.doi.org/10.1371/journal.pone.0015904

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