Cargando…

Thrombin Induces Macrophage Migration Inhibitory Factor Release and Upregulation in Urothelium: A Possible Contribution to Bladder Inflammation

PURPOSE: Macrophage migration inhibitory factor (MIF) is a pro-inflammatory cytokine expressed by urothelial cells that mediates bladder inflammation. We investigated the effect of stimulation with thrombin, a Protease Activated Receptor-1 (PAR1) agonist, on MIF release and MIF mRNA upregulation in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Vera, Pedro L., Wolfe, Terra E., Braley, Alexander E., Meyer-Siegler, Katherine L.
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013117/ https://www.ncbi.nlm.nih.gov/pubmed/21209875 http://dx.doi.org/10.1371/journal.pone.0015904

Ejemplares similares

Macrophage Migration Inhibitory Factor Mediates PAR-Induced Bladder Pain
por: Kouzoukas, Dimitrios E., et al.
Publicado: (2015)

Substance P induces localization of MIF/α1-inhibitor-3 complexes to umbrella cells via paracellular transit through the urothelium in the rat bladder
por: Vera, Pedro L, et al.
Publicado: (2006)

Inhibition of macrophage migration inhibitory factor decreases proliferation and cytokine expression in bladder cancer cells
por: Meyer-Siegler, Katherine L, et al.
Publicado: (2004)

Removal of urothelium affects bladder contractility and release of ATP but not release of NO in rat urinary bladder
por: Munoz, Alvaro, et al.
Publicado: (2010)

Cyclophosphamide-Induced Cystitis Increases Bladder CXCR4 Expression and CXCR4-Macrophage Migration Inhibitory Factor Association
por: Vera, Pedro L., et al.
Publicado: (2008)

Cascade Bioassay Evidence for the Existence of Urothelium-Derived Inhibitory Factor in Guinea Pig Urinary Bladder
por: Guan, Na N., et al.
Publicado: (2014)

Intravesical CD74 and CXCR4, macrophage migration inhibitory factor (MIF) receptors, mediate bladder pain
por: Ye, Shaojing, et al.
Publicado: (2021)

Further evidence for increased macrophage migration inhibitory factor expression in prostate cancer
por: Meyer-Siegler, Katherine L, et al.
Publicado: (2005)

Anatomical location of Macrophage Migration Inhibitory Factor in urogenital tissues, peripheral ganglia and lumbosacral spinal cord of the rat
por: Vera, Pedro L, et al.
Publicado: (2003)

Macrophage migration inhibitory factor mediates protease‐activated receptor 4‐induced bladder pain through urothelial high mobility group box 1
por: Ma, Fei, et al.
Publicado: (2017)

BCG Induced Necrosis of the Entire Bladder Urothelium
por: Krönig, Malte, et al.
Publicado: (2015)

Association between macrophage migration inhibitory factor promoter region polymorphism (-173 G/C) and cancer: a meta-analysis
por: Vera, Pedro L, et al.
Publicado: (2011)

Biopsies of the normal-appearing urothelium in primary bladder cancer
por: Librenjak, Davor, et al.
Publicado: (2010)

Recent Advances in the Biology of the Urothelium and Applications for Urinary Bladder Dysfunction
por: Romih, Rok, et al.
Publicado: (2014)

Role of ERK signaling in bladder urothelium in response to cyclophosphamide injury
por: Narla, Sridhar Tatarao, et al.
Publicado: (2022)

Substance P Increases Cell-Surface Expression of CD74 (Receptor for Macrophage Migration Inhibitory Factor): In Vivo Biotinylation of Urothelial Cell-Surface Proteins
por: Meyer-Siegler, Katherine L., et al.
Publicado: (2009)

AB274. SPR-01 Mechanosensitive release of adenosine 5'-triphosphate and other purines from the bladder urothelium
por: Mutafova-Yambolieva, Violeta N., et al.
Publicado: (2016)

P2Y Receptor Modulation of ATP Release in the Urothelium
por: Mansfield, Kylie J., et al.
Publicado: (2014)

Increased expression of neuregulin 1 in the urothelium of rat bladder with partial bladder outlet obstruction
por: Yang, Seung Woo, et al.
Publicado: (2017)

The use of multispectral imaging to distinguish reactive urothelium from neoplastic urothelium
por: Gilbert, Christopher Michael, et al.
Publicado: (2010)

Urothelium-Specific Deletion of Connexin43 in the Mouse Urinary Bladder Alters Distension-Induced ATP Release and Voiding Behavior
por: Kono, Jin, et al.
Publicado: (2021)

Bladder Oxidative Stress and HMGB1 Release Contribute to PAR4-Mediated Bladder Pain in Mice
por: Ye, Shaojing, et al.
Publicado: (2022)

Signalling Molecules in the Urothelium
por: Winder, Michael, et al.
Publicado: (2014)

Immunohistochemistry as a paramount tool in research of normal urothelium, bladder cancer and bladder pain syndrome
por: Zupančič, Daša, et al.
Publicado: (2021)

Circadian coordination of ATP release in the urothelium via connexin43 hemichannels
por: Sengiku, Atsushi, et al.
Publicado: (2018)

Aging-Associated Changes in Oxidative Stress Negatively Impacts the Urinary Bladder Urothelium
por: de Rijk, Mathijs M., et al.
Publicado: (2022)

Urinary ATP Levels Are Controlled by Nucleotidases Released from the Urothelium in a Regulated Manner
por: Gutierrez Cruz, Alejandro, et al.
Publicado: (2022)

Overexpression of Aquaporin-1 and Caveolin-1 in the Rat Urinary Bladder Urothelium Following Bladder Outlet Obstruction
por: Kim, Sun-Ouck, et al.
Publicado: (2013)

Early and late morphological changes (including carcinoma of the urothelium) induced by irradiation of the rat urinary bladder.
por: Antonakopoulos, G. N., et al.
Publicado: (1982)

Phospho-mTOR in non-tumour and tumour bladder urothelium: Pattern of expression and impact on urothelial bladder cancer patients
por: AFONSO, JULIETA, et al.
Publicado: (2014)

Purinergic and muscarinic modulation of ATP release from the urothelium and its paracrine actions
por: Sui, Guiping, et al.
Publicado: (2013)

Tumorigenicity of RTK/RAS in urothelium
por: Wu, Xue-Ru, et al.
Publicado: (2015)

Does the Urothelium of Old Mice Regenerate after Chitosan Injury as Quickly as the Urothelium of Young Mice?
por: Erzar, Eva, et al.
Publicado: (2020)

Unusual finding of endocervical-like mucinous epithelium in continuity with urothelium in endocervicosis of the urinary bladder
por: Cheah, Phaik-Leng, et al.
Publicado: (2011)

Directed differentiation of human induced pluripotent stem cells into mature stratified bladder urothelium
por: Suzuki, Kotaro, et al.
Publicado: (2019)

Changes in uroplakin expression in the urothelium of patients with ulcerative interstitial cystitis/bladder pain syndrome
por: Cho, Kang Jun, et al.
Publicado: (2020)

Targeted-sequence of normal urothelium and tumor of patients with non-muscle invasive bladder cancer
por: Hayashi, Yujiro, et al.
Publicado: (2022)

Mutation Hotspots Found in Bladder Cancer Aid Prediction of Carcinogenic Risk in Normal Urothelium
por: Grant, Sydney R., et al.
Publicado: (2023)

Thrombin acts as inducer of proinflammatory macrophage migration inhibitory factor in astrocytes following rat spinal cord injury
por: Yang, Ting, et al.
Publicado: (2022)

A study of cytokeratin 20 immunostaining in the urothelium of neuropathic bladder of patients with spinal cord injury
por: Vaidyanathan, Subramanian, et al.
Publicado: (2002)

Cannot write session to /tmp/vufind_sessions/sess_udvqggi5icbmet9ic7c5tllvb4