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Evolutionary Distances in the Twilight Zone—A Rational Kernel Approach
Phylogenetic tree reconstruction is traditionally based on multiple sequence alignments (MSAs) and heavily depends on the validity of this information bottleneck. With increasing sequence divergence, the quality of MSAs decays quickly. Alignment-free methods, on the other hand, are based on abstract...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013127/ https://www.ncbi.nlm.nih.gov/pubmed/21209825 http://dx.doi.org/10.1371/journal.pone.0015788 |