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p53 Upregulation Is a Frequent Response to Deficiency of Cell-Essential Genes
BACKGROUND: The role of p53 in the prevention of development of embryos damaged by genotoxic factors is well recognized. However, whether p53 plays an analogous role in preventing birth defects from genetic mutations remains an unanswered question. Genetic screens for mutations affecting development...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013139/ https://www.ncbi.nlm.nih.gov/pubmed/21209837 http://dx.doi.org/10.1371/journal.pone.0015938 |