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p53 Upregulation Is a Frequent Response to Deficiency of Cell-Essential Genes

BACKGROUND: The role of p53 in the prevention of development of embryos damaged by genotoxic factors is well recognized. However, whether p53 plays an analogous role in preventing birth defects from genetic mutations remains an unanswered question. Genetic screens for mutations affecting development...

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Detalles Bibliográficos
Autores principales:	Danilova, Nadia, Kumagai, Asako, Lin, Jenny
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3013139/ https://www.ncbi.nlm.nih.gov/pubmed/21209837 http://dx.doi.org/10.1371/journal.pone.0015938

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