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Dual roles of Drosophila p53 in cell death and cell differentiation

The mammalian p53-family consists of p53, p63 and p73. While p53 accounts for tumor suppression through cell cycle arrest and apoptosis, the functions of p63 and p73 are more diverse and also include control of cell differentiation. The Drosophila genome contains only one p53 homolog, Dp53. Previous...

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Detalles Bibliográficos
Autores principales: Fan, Yun, Lee, Tom V., Xu, Dongbin, Chen, Zhihong, Lamblin, Anne-Francoise, Steller, Hermann, Bergmann, Andreas
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014827/
https://www.ncbi.nlm.nih.gov/pubmed/19960025
http://dx.doi.org/10.1038/cdd.2009.182