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The GPR55 agonist lysophosphatidylinositol acts as an intracellular messenger and bidirectionally modulates Ca(2+)-activated large-conductance K(+) channels in endothelial cells
Lysophospholipids are known to serve as intra- and extracellular messengers affecting many physiological processes. Lysophosphatidylinositol (LPI), which is produced in endothelial cells, acts as an endogenous agonist of the orphan receptor, G protein-coupled receptor 55 (GPR55). Stimulation of GPR5...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
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Springer-Verlag
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014879/ https://www.ncbi.nlm.nih.gov/pubmed/21072666 http://dx.doi.org/10.1007/s00424-010-0898-x |