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The GPR55 agonist lysophosphatidylinositol acts as an intracellular messenger and bidirectionally modulates Ca(2+)-activated large-conductance K(+) channels in endothelial cells

Lysophospholipids are known to serve as intra- and extracellular messengers affecting many physiological processes. Lysophosphatidylinositol (LPI), which is produced in endothelial cells, acts as an endogenous agonist of the orphan receptor, G protein-coupled receptor 55 (GPR55). Stimulation of GPR5...

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Detalles Bibliográficos
Autores principales: Bondarenko, Alexander I., Malli, Rolland, Graier, Wolfgang F.
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014879/
https://www.ncbi.nlm.nih.gov/pubmed/21072666
http://dx.doi.org/10.1007/s00424-010-0898-x