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Targeting the oncogenic protein beta-catenin to enhance chemotherapy outcome against solid human cancers
BACKGROUND: Beta-catenin is a multifunctional oncogenic protein that contributes fundamentally to cell development and biology. Elevation in expression and activity of β-catenin has been implicated in many cancers and associated with poor prognosis. Beta-catenin is degraded in the cytoplasm by glyco...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014904/ https://www.ncbi.nlm.nih.gov/pubmed/21126356 http://dx.doi.org/10.1186/1476-4598-9-310 |