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Targeting the oncogenic protein beta-catenin to enhance chemotherapy outcome against solid human cancers

BACKGROUND: Beta-catenin is a multifunctional oncogenic protein that contributes fundamentally to cell development and biology. Elevation in expression and activity of β-catenin has been implicated in many cancers and associated with poor prognosis. Beta-catenin is degraded in the cytoplasm by glyco...

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Detalles Bibliográficos
Autores principales:	Saifo, Maher S, Rempinski, Donald R, Rustum, Youcef M, Azrak, Rami G
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014904/ https://www.ncbi.nlm.nih.gov/pubmed/21126356 http://dx.doi.org/10.1186/1476-4598-9-310

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