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CD4(+) T Cells Modulate Expansion and Survival but Not Functional Properties of Effector and Memory CD8(+) T Cells Induced by Malaria Sporozoites
CD4(+) helper T cells are critical orchestrators of immune responses to infection and vaccination. During primary responses, naïve CD8(+) T cells may need “CD4 help” for optimal development of memory populations. The immunological factors attributed to CD4 help depend on the context of immunization...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014941/ https://www.ncbi.nlm.nih.gov/pubmed/21245909 http://dx.doi.org/10.1371/journal.pone.0015948 |