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Towards Delineating Functions within the Fasciola Secreted Cathepsin L Protease Family by Integrating In Vivo Based Sub-Proteomics and Phylogenetics

BACKGROUND: Fasciola hepatica, along with Fasciola gigantica, is the causative agent of fasciolosis, a foodborne zoonotic disease affecting grazing animals and humans worldwide. Pathology is directly related to the release of parasite proteins that facilitate establishment within the host. The domin...

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Detalles Bibliográficos
Autores principales: Morphew, Russell M., Wright, Hazel A., LaCourse, E. James, Porter, Joanne, Barrett, John, Woods, Debra J., Brophy, Peter M.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014944/
https://www.ncbi.nlm.nih.gov/pubmed/21245911
http://dx.doi.org/10.1371/journal.pntd.0000937