Bovine proteins containing poly-glutamine repeats are often polymorphic and enriched for components of transcriptional regulatory complexes

BACKGROUND: About forty human diseases are caused by repeat instability mutations. A distinct subset of these diseases is the result of extreme expansions of polymorphic trinucleotide repeats; typically CAG repeats encoding poly-glutamine (poly-Q) tracts in proteins. Polymorphic repeat length variat...

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Detalles Bibliográficos
Autores principales: Whan, Vicki, Hobbs, Matthew, McWilliam, Sean, Lynn, David J, Lutzow, Ylva Strandberg, Khatkar, Mehar, Barendse, William, Raadsma, Herman, Tellam, Ross L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014979/
https://www.ncbi.nlm.nih.gov/pubmed/21092319
http://dx.doi.org/10.1186/1471-2164-11-654

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3014979/
https://www.ncbi.nlm.nih.gov/pubmed/21092319
http://dx.doi.org/10.1186/1471-2164-11-654

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